UMI or not UMI, that is the question for scRNA-seq zero-inflation thumbnail

UMI or not UMI, that is the question for scRNA-seq zero-inflation

Fig. 1: A comparison of the effect of UMI use and the sequencing platform on zero-inflation.


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We thank Deutsche Forschungsgemeinschaft for funding (grants KU1315/14-1 and HO1582/12-1).

Author information


  1. Bioinformatics and Computational Biophysics, Faculty of Biology and Center for Medical Biotechnology, University of Duisburg-Essen, Essen, Germany

    Yingying Cao, Simo Kitanovski & Daniel Hoffmann

  2. Institute of Cell Biology (Cancer Research), University Hospital Essen, Essen, Germany

    Ralf Küppers


Y.C. analyzed data and wrote the first draft, S.K. and R.K. reviewed work and revised the text, D.H. supervised work and wrote the final text.

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Correspondence to
Daniel Hoffmann.

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Cao, Y., Kitanovski, S., Küppers, R. et al. UMI or not UMI, that is the question for scRNA-seq zero-inflation.
Nat Biotechnol (2021).

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